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CLD...process of progressive destruction and regeneration of the liver parenchyma leading to fibrosis and cirrhosis.
CLD refers to disease of the liver which lasts over a period of six months. قد يحصل فيه
Inflamtion.heptitis .or hcc..
Cause حق cld
Viral...فيروس b and c and other like CMV -EPV-YELOWfever
٢_drugs and toxins مثل كحولات وادويه
methotrexate, amiodarone, nitrofurantoin and
racetamol (acetaminophen) causes acute liver
3-Metabolic
Non-alcoholic fatty liver disease
Haemochromatosis
Wilson's Disease
Autoimmune
Autoimmune hepatitis
Primary biliary cholangitis (primary biliary cirrhosis)
Primary sclerosing cholangitis
Right heart failure
الان نتكلم عن المضاعفات ....
Portal hypertension
Ascites
Hypersplenism (with or without splenomegaly)
Lower oesophageal varices and rectal varices
Synthetic dysfunction
Hypoalbuminaemia
Coagulopathy
Hepatopulmonary syndrome
Hepatorenal syndrome
Encephalopathy
Hepatocellular carcinoma
وبعدين ايش نشوف في حالات CLD ياشباب راح نشوف
التالي sign
Clubbing
Palmar erythema
Spider nevi (angiomata)
Gynaecomastia
Feminising hair distribution
Testicular atrophy
Small irregular shrunken liver
Anaemia
Caput medusae
في حاجه اسمها decompensation
وcompensation .....
Decompensation كالتالي يحصل عند المريض ذولا الحاجات
Drowsiness (encephalopathy)
Hyperventilation (encephalopathy)
Metabolic flap/asterixis (encephalopathy)
Jaundice (excretory dysfunction)
Ascites (portal hypertension and hypoalbuminaemia)
Leukonychia (hypoalbuminaemia)
Peripheral oedema (hypoalbuminaemia)
Bruising (coagulopathy)
Acid-base imbalance, most commonly respiratory alkalosis
والباقي بانكمله .....يتبع 😊)s.n.s
BY مذكرة طالب في الطب🧑⚕👩⚕
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