NEUROCOGNITIONANDLEARNING Telegram 5618
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Noisy Synaptic Conductance: Bug or a Feature? ▪️More often than not, action potentials fail to trigger neurotransmitter release. And even when neurotransmitter is released, the resulting change in synaptic conductance is highly variable. Given the energetic…
▪️Synaptic transmission is noisy, partially because neurotransmitter release is unreliable but also because synaptic receptor current varies stochastically.
When synaptic input is below the cell spike threshold, adding noise may push it above the threshold, thus improving information transmission.
Synaptic noise can widen the dynamic range of transmission.
Synaptic noise allows synapses to communicate their degree of uncertainty.
Noise is a ubiquitous feature of brain activity and is likely to be a critical element in any theory of how the brain works.

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▪️Synaptic transmission is noisy, partially because neurotransmitter release is unreliable but also because synaptic receptor current varies stochastically.
When synaptic input is below the cell spike threshold, adding noise may push it above the threshold, thus improving information transmission.
Synaptic noise can widen the dynamic range of transmission.
Synaptic noise allows synapses to communicate their degree of uncertainty.
Noise is a ubiquitous feature of brain activity and is likely to be a critical element in any theory of how the brain works.

🆔@neurocognitionandlearning

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