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CRISPR/Cas9 revitalizes adoptive T-cell therapy for cancer immunotherapy

New Paper by USERN Interest Groups

🌀Adoptive T-cell therapy (ACT) is one of the most distinctive modalities of this therapeutic approach, which seeks to harness the potential of combating cancer cells by using autologous or allogenic tumor-specific T-cells.

🌀Here, we aim to review and categorize the recent breakthroughs of genetically modified TCR/CAR T-cells through CRISPR/Cas9 technology and address the pearls and pitfalls of each method.

Source: https://doi.org/10.1186/s13046-021-02076-5

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@cip_usern



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CRISPR/Cas9 revitalizes adoptive T-cell therapy for cancer immunotherapy

New Paper by USERN Interest Groups

🌀Adoptive T-cell therapy (ACT) is one of the most distinctive modalities of this therapeutic approach, which seeks to harness the potential of combating cancer cells by using autologous or allogenic tumor-specific T-cells.

🌀Here, we aim to review and categorize the recent breakthroughs of genetically modified TCR/CAR T-cells through CRISPR/Cas9 technology and address the pearls and pitfalls of each method.

Source: https://doi.org/10.1186/s13046-021-02076-5

@niima_usern
@cip_usern

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