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🔹Importance of TNF-alpha and its alterations in the development of cancers
📄 New Paper by CIP
🧩TNF-alphaα plays a role in pathogenesis of many diseases, including malignancies. This makes TNF-α a promising therapeutic target.
🧩TNF-α also participates in apoptosis and necrosis, angiogenesis and cellular migration.
🧩TNF-α exerts cancerogenesis via its receptors and other cytokines in its signaling pathways.
🧩TNF-α is a double-edged sword due to its paradoxical effects encountering with neoplasms.
🧩Anti-neoplastic therapies based on TNF-α must address its miscellaneous signaling pathways.
https://www.sciencedirect.com/science/article/abs/pii/S104346662030082X
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BY CIP, Cancer Immunology Project
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